Latinx (pronounced La-teen-ex) is the gender-neutral term that covers the largest racial minority in the United States, and the poorest but fastest-growing American group, whose political empowerment is altering the balance of forces in a growing number of states. In this groundbreaking discussion, Ed Morales explains how Latinx political identities are tied to a long Latin American history of mestizaje, translatable as mixedness or hybridity, and that this border thinking is both a key to understanding Latinx cultures and a challenge to Americas infamously blackwhite racial regime.